Tammy's skin removal surgery is still up in the air as she struggles to kick bad habits. Amy's got a new roommate and a new man. Chris' plays referee between Brittany and their new neighbor. Tammy is keeping a secret from her family.

Tammy gets a push to reveal her personal life to her family. Amy's life gets even more chaotic, pushing her to make a rash decision. Chris and his wife make a big decision about her health.

Tammy reveals to her sisters that she's dating a woman and their reaction surprises her. Chris and Tammy check-in on their skin removal progress, and a harrowing moment at the petting zoo sees Amy's life turned upside down.

Amy reels emotionally and physically from her camel bite and arrest. Chris explores a passion project, and Tammy expands her circle and fulfills a childhood dream.

Tammy takes a big step forward in her relationship with Andrea.

When the siblings react to Amy's proposal, relationships are fractured.

Tammy addresses Amy about her weight gain and the family heads to Pittsburgh for Tammy's skin removal surgery.

A missing tool in the operating room causes delays to Tammy's extreme skin removal and Amy decides she's had enough and makes a bold move.

The family takes a trip down memory lane and revisits the important people and places who have made them who they are today, but not without jokes and hilarity along the way.