The story takes place in a universe where most of the superpowered individuals are recognized as superheroes, but in reality abuse their powers for personal gain, information the public is kept unaware of.

The even more intense, more insane season two finds The Boys on the run from the law, hunted by the Supes, and desperately trying to regroup and fight back against Vought. In hiding, Hughie, Mother’s Milk, Frenchie and Kimiko try to adjust to a new normal, with Butcher nowhere to be found. Meanwhile, Starlight must navigate her place in The Seven as Homelander sets his sights on taking complete control. His power is threatened with the addition of Stormfront, a social media-savvy new Supe, who has an agenda of her own. On top of that, the Supervillain threat takes center stage and makes waves as Vought seeks to capitalize on the nation’s paranoia.

It’s been a year of calm. Homelander’s subdued. Butcher works for the government, supervised by Hughie of all people. But both men itch to turn this peace and quiet into blood and bone. So when The Boys learn of a mysterious Anti-Supe weapon, it sends them crashing into the Seven, starting a war, and chasing the legend of the first Superhero: Soldier Boy.

The world is on the brink. Victoria Neuman is closer than ever to the Oval Office and under Homelander's muscly thumb as he consolidates his power. Butcher, with only months to live, has lost Becca's son, and his job as The Boys' leader. The rest of the team are fed up with his lies. With the stakes higher than ever, they must find a way to work together and save the world before it's too late.

It’s Homelander’s world, completely subject to his erratic, egomaniacal whims. Hughie, Mother’s Milk, and Frenchie are imprisoned in a “Freedom Camp.” Annie struggles to mount a resistance against the overwhelming Supe force. Kimiko is nowhere to be found. But when Butcher reappears, ready and willing to use a virus that will wipe all Supes off the map, he sets in motion a chain of events that will forever change the world and everyone in it.