What happens when a drunken promise leads to living with a dragon? That’s Miss Kobayashi’s new reality when Tohru appears in her life. With a maid-slash-dragon in her home, she’s experiencing a whole new level of domestic bliss! But the dragons don’t stop there. On a mission to find Tohru appears Kanna, a little dragon with a big attitude. Before she knows it, Kobayashi’s got a house full of dragons—one serving tail and the other serving serious moe! Together, they live side by side with only the occasional disaster…well, maybe. But nothing beats coming home to the warm welcome of a dragon maid!

A strange turn of events leads the Dragon, Tohru, to work as Miss Kobayashi's maid. She occasionally (that's a lie, she often) causes trouble for her beloved Miss Kobayashi while blending into human society and splendidly (that's a lie, only mediocrely) carrying out her maid duties. Her fellow dragons, Kanna, Lucoa, Fafnir, and Elma all find their own places to fit in as well and enjoy interspecies interactions with the humans. Yet while they're all enjoying that laid-back and occasionally turbulent left, the threat of a new Dragon swoops down upon Miss Kobayashi.