The year is 2095. Magic has been tamed as another form of technology, and the practice of magic is now a rigorous discipline. Brother and sister Tatsuya and Miyuki Shiba are just about to start their first year at the renowned First Magic High School of Japan. But the school's ironclad rules mean that the brilliant Miyuki enters the prestigious Course 1, while her older brother, Tatsuya, is relegated to Course 2--and that's just the beginning of their troubles!

Miyuki Shiba’s classmate Kitayama Shizuku is on her way to study abroad. For magicians, this is normally impossible, since allowing the genes of someone who can use magic outside their home country’s borders is tantamount to giving up national secrets. But it’s allowed to happen in one case—exchange programs. And that’s how Angelina Kudou Shields, known as Lina, has arrived in Japan from the USNA to study at First High. Around the time Lina arrived in Japan, magicians began getting attacked by a mysterious being who leaves his victims drained of blood. Will Tatsuya and Miyuki Shiba be able to discover the identity of the “Vampire”?

After the battle against The New Breed Front, Tatsuya and Miyuki enter the new "Magic Engineering Department."