Barbara Naklicki holds off a full two days before reporting the disappearance of her husband, Ed. The first clue is a dire one: Ed's work van has been found in a forest preserve on the city's edge. Next, Detective Bob Berent gets a strange phone call from a hotel on Michigan Avenue, Chicago's main shopping drag. The hotel reports a guest took a room three nights ago--and vanished.

Police detectives investigate the subculture of Chicago's black gay males when a young man leaves a disturbing voice mail message and then goes missing.

A man reports that his missing girlfriend left him an ominous phone call; a Chicago teenager falls under the influence of a gang member considered to be armed and dangerous.

Detectives search for an elderly woman who vanished after returning from a doctor's appointment, with the suspicion that the use of pain medication may have contributed to her disappearance.

A young man claiming to be an eyewitness in the shooting death of a 17-year-old Texas girl makes an unusual deal with prosecutors.