Season 1 of My Wife and Kids premiered on March 28, 2001.

Season 2 of My Wife and Kids premiered on September 26, 2001.

Season 3 of My Wife and Kids premiered on September 25, 2002.

Season 4 of My Wife and Kids premiered on September 24, 2003.

Season 5 of My Wife and Kids premiered on September 21, 2004.