At Leeds General Infirmary, Professor Simon Kay stands ready to perform a rare double hand transplant; in neurosurgery, Kenan Deniz has two patients needing urgent brain surgery.

Surgeon Naved Alizai operates on two children needing urgent liver surgery, and endocrine consultants Sheila Fraser and Emma Collins prepare to remove a tumour from a patient’s neck.

Neurosurgeon Ryan Mathew must rebuild a man’s missing skull, and consultant Sheila Fraser removes a football-sized tumour from a patient’s abdomen, suspected to be cancerous.

Plastic surgeon Chris West stops an anxious cancer patient from leaving, and neurosurgeon Kenan Deniz operates on a rare tumour behind a patient’s ear that could paralyse her face.

Cardiac Surgeon Betsy Evans operates on her longest-waiting patient, and Professor Simon Kay aims to perform hand surgery on a teenage patient whose fingers are bent inwards.

Surgeon Kostas Papagiannopoulos must investigate a suspicious growth on a patient’s lung, and cardiologist Andrew Hogarth treats a patient with a life-threatening infection.

Cardiac surgeon Betsy Evans operates on a patient needing a critical double bypass, and neurosurgeon Ryan Mathew performs awake brain surgery on a patient with a growing tumour.

Children’s heart surgeon Osama Jaber must perform life-saving surgery on a 15-day-old baby, and neurosurgeon Kenan Deniz operates on a patient suffering from debilitating headaches.