Taking an interdisciplinary approach to the history of science and invention, Connections explores an "Alternative View of Change" that rejects the conventional linear and teleological view of historical progress. To demonstrate this view, Burke begins each episode with a particular event or innovation in the past (usually ancient or medieval) and traces a path from that event through a series of connections to a fundamental and essential aspect of the modern world.

Sequel series to the 1979 "Connections" where historian James Burke walks the viewer through the tenuous threads of history that link seemingly obscure scientific breakthroughs and the events and products that we have today.

In the conclusion to his groundbreaking series, James Burke continues to make incredible connections to history's most important discoveries and inventions.