It's been ten years since the creation of the Great Truce, an elaborate joint-species surveillance system designed and monitored by cats and dogs to keep the peace when conflicts arise. But when a tech-savvy villain hacks into wireless networks to use frequencies only heard by cats and dogs, he manipulates them into conflict and the worldwide battle between cats and dogs is BACK ON. Now, a team of inexperienced and untested agents will have to use their old-school animal instincts to restore order and peace between cats and dogs everywhere.

When a professor develops a vaccine that eliminates human allergies to dogs, he unwittingly upsets the fragile balance of power between cats and dogs and touches off an epic battle for pet supremacy. The fur flies as the feline faction, led by Mr. Tinkles, squares off against wide-eyed puppy Lou and his canine cohorts.

The ongoing war between the canine and feline species is put on hold when they join forces to thwart a rogue cat spy with her own sinister plans for conquest.