Joe Palooka is a naive young man whose father Pete was a champion boxer, but his lifestyle caused Joe's mother Mayme to leave him and to take young Joe to the country to raise him.

After losing heavyweight contender Al Costa to mob boss Florini fight promoter Knobby Walsh recruits small town boy Joe Palooka to take his place. First in the series.

In the second film of Monogram's Joe Palooka series, Joe is 'used', by two state senators scheming to obtain oil-rich lands, in a publicity campaign to get the land transferred to the state, supposedly for a park. When Joe learns that he has been used as a dupe he becomes disillusioned and leaves the prize=fighting profession. But, his manager, sparring partners, and fiancée manage to expose the land-grab scheme, clear Joe's name and discredit the crooked politicians.

The third of the Monogram series based on Ham Fisher's "Joe Palooka" comic strip, opens with Knobby Walsh, the manager of Joe Palooka trying to talk his way out of a traffic citation, and the story leading to that point is told in flashback as narrated by Walsh. Heavyweight champion Joe, after knocking out an opponent who later died in his dressing room, feels responsible and threatens to give up boxing. But the dead fighter's fiance thinks he died as the result of a drug that was given to him by a gang of gamblers, who made a rich haul betting on Palooka. Joe, Knobby and the police unite to run down the gamblers, but not before Joe also is nearly murdered by the same means...a poisoned mouthpiece. Elyse Knox is along as Joe's sweetheart Anne Howe, although Anne and Joe had long been married in the comic strip.

Joe is scheduled for the big fight as usual. This one has more fight sequences than plot.

Gangsters frame Joe on a drunk charge and a murder rap so they can put their own fighter into a big event. Joe investigates in an attempt to prove his innocence.

Joe heads for South America to fight the Latin champ. Shipboard, he helps federal agents fight counterfeiters. He also spars with love interest Anne Howe.

Newlyweds Joe and Anne Palooka are delayed in their honeymoon plans by the helpful Humphrey Pennyworth and by considerably-less-helpful manager, Knobby Walsh.

A crooked boxing promoter tries to shake down Joe's manager by setting up a rigged fight in Humphrey Pennyworth's hometown.

Joe Palooka encounters gangsters and tries to alert the law.

Joe Palooka and two friends are taking hostage by three criminals.

Joe Palooka goes blind during a fight. An operation restores his vision, but he's told not to fight for a year. His trainer Knobby has picked up another fighter, but gangsters are pressing him to fix fights. Joe decides to risk his eyesight to save Knobby's honor.