Akira Hojo and Chiaki Asami live different lives in Tokyo, Japan: Hojo is the leader of a small but rising Yakuza clan, while Asami is a politician aiming to become the youngest member of the Japanese parliament. But while they both live in different ways, Hojo and Asami share the same past; both of them were survivors of the Killing Fields of Cambodia. With the aggression and survival instincts they learned in the Cambodian jungles, Hojo and Asami strive in both the Yakuza and political world to reform Japan into their own sanctuary.

Two people who lead Japan to "Sanctuary". Hojo aims to unite the Yakuza organization in the Kanto region, and Asami to create a faction "Rifukakai," aiming to destroy Isaoka's system of the ruling Democratic Party. Meanwhile, the connection between Hojo and Asami is revealed.

Standing in the way of Hojo and Asami is Secretary-General Isaoka, and a new enemy, the Russian Mafia. The magnificent war between front and back society has finally reached its climax! What is the incurable disease that hit Asami when the secret bond between the two was revealed? Two men work to transform their lives and reshape Japan.