Will Mannon, "product of the Devil's loins", is released from a frontier prison and promptly goes in search of the people who put him there around twelve years ago, Marshal Matt Dillon and Miss Kitty Russell.

James Arness rides again as Matt Dillon, the US Marshal he made popular in the 1955-75 TV series. In this movie he goes after a renegade Apache named Wolf who has taken his daughter captive. As a bargaining chip, Dillon helps two sons of Apache chief Geronimo out of the fort stockade and offers them in trade. Dillon is aided by an Army scout, Chalk Brighton.

Retired marshal Dillon goes after a 15 year old boy who is determined to kill the men responsible for the murder of his mother during a stagecoach robbery

For thirty years, Marshall Matt Dillon fought to preserve the law in Dodge City… now, he's wanted for murder and fighting to clear his name. Three deputies ride up with a warrant for Dillon's arrest, a wealthy mine operator has been gunned down in cold blood and an eyewitness says Dillon was the murderer.

Retired marshal Matt Dillon tracks Arizona rustlers and lands in the middle of the 1880s Pleasant Valley War.