In the second part of the German remake of the Winnetou films, Winnetou's sister Nscho Tschi is kidnapped by a brutal crook who wants to find a mythical Apache treasure. Old Shatterhead and Winnetou get forced to search for the precious in the silver sea by their evil opponent El Mas Loco.

In Part Three, entitled "The Last Fight," gangster Santer Jr. attempts to seize an oil well on Indian territory. To prevent this, Winnetou and Old Shatterhand must reconcile the warring Indian tribes so that they can take up the fight against the henchmen of the criminal.

The first part, "A New World", tells how the young German engineer Karl May comes to America and starts to work for a railway company in the Wild West. Under dramatic circumstances, he meets Apache chief Winnetou and becomes friends with him and his tribe. The Apaches give it the name Old Shatterhand. Together they fight now against the unscrupulous henchmen of the railway company, who wants to lay a route through the Indian area.