A student moves into a run-down building in New York City. His bizarre neighbors make a concoction in their apartment they call wine, but when he takes some of it, he turns into a deformed, murderous monster.

A dirty bomb has decimated New York City’s financial district and reduced midtown to a post-apocalyptic nightmare. The neighborhood known as Slime City has been evacuated, except for the homeless, and in the ruins of a soup kitchen four squatters discover a supply of food that transforms them into hideous slime creatures, driven to murder! Meanwhile, a greedy developer who has set his sights on Slime City hires a team of mercenaries to wipe out the creatures.