After witnessing a brutal massacre, the legendary hero Sartana is ready to do some investigating. Almost everyone in the tiny town of Indian Creek seems eager to buy up the property left behind by the murder victims, and one of them could well be behind the killings. The sheriff himself is not above suspicion, so Sartana must uncover the culprit all on his own.

Sartana is falsely accused of robbing a bank, and must find the real robbers and clear his name.

After a stagecoach is robbed and the passengers murdered, a long and tangled series of surprise attacks and murderous double-crosses, leaves the coach's strongbox in the hands of the killer Lasky. It is up to the legendary hero Sartana to track down the missing money and determine just who is ultimately behind the grisly robberies and killings.

Wily roving gunslinger Sartana arrives in a small town and tries to find a hidden fortune of half a million dollars in gold and two million dollars in counterfeit money. Naturally, a bunch of other treacherous folks who include conniving widow Senora Manassas, shrewd fellow gunslinger Grand Full, and the vicious and unhinged General Monk are also looking to get their greedy hands on said fortune.

Sartana, bounty hunter and gunfighter, witnesses the robbery of a shipment of gold. He finds his way into town where he meets with a lot of suspicious stares from the locals. He also meets with Samuel Spencer, who seems to own the company in this company town. The gold shipments are being stolen, so Spencer agrees to hire Sartana to protect the next gold shipment. Numerous dull-witted villains make attempts on Sartana's life, but he survives. Eventually, Sartana's nemesis Sabbath (he of the white coat and parasol) rides into town. With a showdown inevitable, Sartana and Sabbath square off to settle the score.