After the older DigiDestined are abducted by the mysterious Kokomon, the next generation of kids team up with American DigiDestined Willis to rescue them - only to discover that their enigmatic enemy has an unexpected connection to their new friend!

When a powerful new Internet Digimon hatches and begins to consume data at an alarming rate, the Digidestined - kids chosen to save the digital world - must put an end to the destruction before the damage becomes irreversible and worldwide communication halts forever. As computer-based missiles are launched, and a wayward Digimon kidnaps the Digidestined, only the combined efforts of a worldwide network of kids and a new group of "Digidestined" can rescue the others and stop global disaster.

Tai is now a university student, living alone, working hard at school, and working every day, but with his future still undecided. Meanwhile, Matt and others continue to work on Digimon incidents and activities that help people with their partner Digimon. When an unprecedented phenomenon occurs, the DigiDestined discover that when they grow up, their relationship with their partner Digimon will come closer to an end.

In 2012, after the events of Digimon Adventure: Last Evolution Kizuna, the early adulthood DigiDestined—Daisuke, Miyako, Iori, Takeru Takashi, Hikari, and Ken—must reconcile their new responsibilities with their Digimon partners. But Rui Owada, a mysterious young man, appears, claiming to be the first human to partner with a Digimon–Ukkomon. Could Rui really have been the first-ever DigiDestined?