Twins separated at birth, Camryn and Alex meet by chance for the first time on their 21st birthday and discover they're witches with the power to save their homeland of Coventry from the evil that threatens it. But when Camryn leaves Alex to face the darkness alone, will Coventry be doomed? Or will the sisters multiply their magic by standing together?

Reunited witch twins Camryn and Alex adjust to their new life as supernatural beings while at the same time trying to maintain a normal existence in this sequel to the magical Disney Channel original movie Twitches. But they soon find themselves going head to head with the forces of darkness that threaten to destroy their world. Luckily, their birth mother, the powerful Miranda, is on hand to help out.