Lenore and Frank Davis are about to have their second child. As Lenore gives birth, the newborn vanishes and leaves behind five dead bodies. It's up to the police and Frank to figure out where their mutated child has gone.

Maternity wards echo with the patter of tiny claws as more murderous baby-faced monsters are born. But rather than kill their monstrous off-spring during delivery, cursed parents flee to secret incubation hide-outs.

The mutant babies have been placed by court order on a deserted island. Appalled by the cynicism and exploitation of the children by the legal system and the media, the man responsible for them leads an expedition to the island to free them.