Set in 1955, French secret agent Hubert Bonisseur de La Bath/OSS 117 is sent to Cairo to investigate the disappearance of his best friend and fellow spy Jack Jefferson, only to stumble into a web of international intrigue.

In 1967, OSS 117 is sent to Brazil in order to retrieve a microfilm list of French Nazi sympathizers, only to once again unknowingly set foot into a bigger international intrigue.

1981. Hubert Bonisseur de la Bath, aka OSS 117, is back. For this new mission – more delicate, more dangerous and more torrid than ever – he is forced to team up with a young new colleague, the promising OSS 1001.