Led by Woody, Andy's toys live happily in his room until Andy's birthday brings Buzz Lightyear onto the scene. Afraid of losing his place in Andy's heart, Woody plots against Buzz. But when circumstances separate Buzz and Woody from their owner, the duo eventually learns to put aside their differences.

Andy heads off to Cowboy Camp, leaving his toys to their own devices. Things shift into high gear when an obsessive toy collector named Al McWhiggen, owner of Al's Toy Barn kidnaps Woody. Andy's toys mount a daring rescue mission, Buzz Lightyear meets his match and Woody has to decide where he and his heart truly belong.

Woody, Buzz, and the rest of Andy's toys haven't been played with in years. With Andy about to go to college, the gang find themselves accidentally left at a nefarious day care center. The toys must band together to escape and return home to Andy.

Woody has always been confident about his place in the world and that his priority is taking care of his kid, whether that's Andy or Bonnie. But when Bonnie adds a reluctant new toy called "Forky" to her room, a road trip adventure alongside old and new friends will show Woody how big the world can be for a toy.

When Bonnie receives a Lilypad tablet as a gift and becomes obsessed, Buzz, Woody, Jessie and the rest of the gang's jobs become exponentially harder when they have to go head to head with the all-new threat to playtime.